Concerned about GMO’s? Extraneous DNA…

Several vaccines currently on the market are genetically engineered. For an overview, click here.


Also important to read is Petricciani, 2014: Adventitious agents in viral vaccines: Lessons learned from 4 case studies. (Journal of Biologicals)

But perhaps even more importantly – and as the FDA is well aware – viral vaccines and biological products contain residual DNA from cell substrate that does not belong in your body. Full FDA presentation, including notes pages from the FDA presentation can be downloaded here:  or view slides only, below.

“Vaccines and other biological products manufactured in cells contain contaminating residual DNA derived from that production cell substrate, with the amount and form of this DNA depending mainly on the type of vaccine. The potential risk of this cellular DNA has been debated for over 40 years without resolution. Opinions on residual DNA have varied from it being considered an inert contaminant, and thus its presence should not be deemed to be a risk to vaccine recipients, to it being considered an important risk factor, particularly for vaccines manufactured in certain cell substrates, such as cells derived from tumours or cells that are tumorigenic. We are not of the opinion that DNA can be considered biologically inert, but whether or what risk residual cell-substrate DNA poses remains to be determined. In this paper, we discuss our approaches to address this issue and describe some preliminary work.” Source:-Biological activity of residual cell-substrate DNA (2006).

See also: Spisák S, Solymosi N, Ittzés P, Bodor A, Kondor D, et al. (2013) Complete Genes May Pass from Food to Human Blood. PLoS ONE 8(7): e69805. doi:10.1371/journal.pone.0069805

Full presentation, including notes pages from the FDA presentation can be downloaded here:

Screen shot 2013-08-16 at 12.24.51 PM


This is an area that needs more work. I have started and stopped trying to write something on this subject because it is such a giant undertaking and I never seem to have the time to focus.  Here is my collection.
Additional reading:
Evaluation of the Human Host Range of Bovine and Porcine Viruses that may Contaminate Bovine Serum and Porcine Trypsin Used in the Manufacture of Biological Products (Marcus-Sekura CJ, NIH)
DNA Contamination in HPV Vaccines (ISIS)
GMO’s in medicine and research –
Australia keeps a list of potential GM introductions into the environment, found here: